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Pregnant women who had symptoms consistent with post-traumatic stress disorder (PTSD) and major depressive disorder were four times more likely to deliver preterm than women without symptoms, researchers found.
Previous research has shown that women who took antidepressants and benzodiazepine had higher risk of a preterm delivery, but the risk associated with PTSD and a major depressive episode (OR 4.08, 95% CI 1.27-13.15) was separate from that risk, according to Kimberly Ann Yonkers, MD, of the Yale School of Medicine, and colleagues.
"This risk is greater than, and independent of, antidepressant and benzodiazepine use and is not simply a function of mood or anxiety symptoms," Yonkers and colleagues said in the June 11 issue of JAMA Psychiatry.
http://www.medpagetoday.com/Psychiatry/AnxietyStress/46290
Abstract available at JAMA Psychiatry: http://archpsyc.jamanetwork.com/article.aspx?articleid=1878916
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