A study published in Psychotherapy and Psychosomatics for the first time demonstrates that traumatic stress may induce DNA breakage, but psychotherapy may heal it. Previous research reveals an association between traumatic stress and an increased risk for numerous diseases, including cancer. At the molecular level, stress may increase carcinogenesis via increased DNA damage and impaired DNA repair mechanisms. The authors assessed DNA breakage in peripheral blood mononuclear cells from individuals with post-traumatic stress disorder (PTSD) and measured the cellular capacity to repair single-strand breaks after exposure to ionizing X-radiation. They also investigated the effect of psychotherapy on both DNA breakage and DNA repair.
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