Placebo Response in Antipsychotic Clinical Trials A Meta-analysis

Former Member 10/28/142:04 PM

Conclusions and Relevance The average treatment change associated with placebo treatment in antipsychotic trials increased since 1960, while the change associated with medication treatment decreased. Changes in randomized clinical trials leading to inflation of baseline scores, enrollment of less severely ill participants, and higher expectations of patients may all be responsible.

http://archpsyc.jamanetwork.co...px?articleid=1911295

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